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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984003Generated: November 2, 2026

oxo-(7-triisopropylsilanyloxymethyl-1H-indol-3-yl)-acetic acid methyl ester → 7-[2,5-Dioxo-4-(7-triisopropylsilanyloxymethyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrol-3-yl]-3,4-dihydro-1H-[1,4]diazepino[6,7,1-hi]indole-2-carboxylic Acid Tert-Butyl Ester

https://huagongshe.com/reaction/984003

Reaction equation

Participants

RoleNameHCIDCharge
Reactantoxo-(7-triisopropylsilanyloxymethyl-1H-indol-3-yl)-acetic acid methyl esterHCID 69742759—
Reactant7-Carbamoylmethyl-3,4-dihydro-1H-[1,4]diazepino[6,7,1-hi]indole-2-carboxylic acid tert-butyl esterHCID 69745709—
Product7-[2,5-Dioxo-4-(7-triisopropylsilanyloxymethyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrol-3-yl]-3,4-dihydro-1H-[1,4]diazepino[6,7,1-hi]indole-2-carboxylic Acid Tert-Butyl EsterHCID 69743447—

Reaction Steps

Beginning with 7-Carbamoylmethyl-3,4-dihydro-1H-[1,4]diaze-pino[6,7,1-hi]indole-2-carboxylic acid tert-butyl ester and oxo-(7-triisopropylsilanyloxymethyl-1H-indol-3-yl)-acetic acid methyl ester, the title compound was prepared essentially as described in Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867198B2
Source datasetuspto-grants-2005_03
ORD IDord-818a23efd95c43eba89a9cf316428ff5
Source noteuspto-grants-2005_03