HCID 86759614, compound → HCID 20765964, compound

HRID 984103Notes

Reaction equation

HRID 984103 reaction equation
[CH3:1][O:2][C:3](=[O:18])[CH2:4][CH:5]1[CH2:9][C:8]2[CH:10]=[C:11](S(Cl)(=O)=O)[CH:12]=[CH:13][C:7]=2[O:6]1>[Pd].O1CCCC1>[CH3:1][O:2][C:3](=[O:18])[CH2:4][CH:5]1[CH2:9][C:8]2[CH:10]=[CH:11][CH:12]=[CH:13][C:7]=2[O:6]1

Participants

4

Reactant 1

HCID 86759614HCID 86759614, compound2×

Product 1

HCID 20765964HCID 20765964, compoundYield 99%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

Compound 4B was prepared by hydrogenation of the corresponding tetrahydrofuran derivative catalyzed by 10% Pd/C in 99% yield. MS: MS: 193 (M+1)+. Preparation of (5-Chlorosulfonyl-2,3-dihydro-benzofuran-2-yl)-acetic acid methyl ester (Compound 4C)

Sources & evidence

ORD record
ord-ae9653ab5c2e43c086d11111b0adbedb
Source dataset
uspto-grants-2005_03
Patent number
US06867224B2

Reaction notes

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