HuagongsheHuagongshe Chemistry Print Report · For research reference only
{6-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethylsulfanyl]-3,4-dihydro-2H-quinolin-1-yl}-acetic acid methyl ester → (6-Mercapto-3,4-dihydro-2H-quinolin-1-yl)-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {6-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethylsulfanyl]-3,4-dihydro-2H-quinolin-1-yl}-acetic acid methyl ester | HCID 20765978 | — |
| Reactant | 5-Mercapto-Indan-2-Carboxylic Acid Methyl Ester | HCID 20766012 | — |
| Product | (6-Mercapto-3,4-dihydro-2H-quinolin-1-yl)-acetic acid methyl ester | HCID 20765991 | — |
Reaction Steps
11C was prepared analogously to compound 1C. Used as unpurified oil. MS: 238 (M+1)+. Preparation of {6-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethylsulfanyl]-3,4-dihydro-2H-quinolin-1-yl}-acetic acid methyl ester (Compound 11D)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867224B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-5b14d30734b8450d9e713caa39591935 |
| Source note | uspto-grants-2005_03 |