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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984125Generated: October 31, 2026

5-Mercapto-Indan-2-Carboxylic Acid Methyl Ester → (5-Mercapto-6-methoxy-indan-1-yl)-acetic acid ethyl ester

https://huagongshe.com/reaction/984125

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Mercapto-Indan-2-Carboxylic Acid Methyl EsterHCID 20766012—
Reactant{6-Methoxy-5-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethylsulfanyl]-indan-1-yl}-acetic acid methyl esterHCID 69590840—
Product(5-Mercapto-6-methoxy-indan-1-yl)-acetic acid ethyl esterHCID 20765962—

Reaction Steps

19C was prepared analogously to compound 1C. Used as unpurified oil. MS: 267 (M+1)+. Preparation of {6-Methoxy-5-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethylsulfanyl]-indan-1-yl}-acetic acid methyl ester (Compound 19D)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867224B2
Source datasetuspto-grants-2005_03
ORD IDord-7131c44441034852ac9910532c106e0f
Source noteuspto-grants-2005_03