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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984237Generated: October 29, 2026

P-Anisidine → tert-butyl 4-(4-methoxyanilino)tetrahydro-1(2H)-pyridinecarboxylate

https://huagongshe.com/reaction/984237

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Producttert-butyl 4-(4-methoxyanilino)tetrahydro-1(2H)-pyridinecarboxylateHCID 2776119—

Reaction Steps

1-(tert-Butoxycarbonyl)-4-piperidone (116 g) and p-anisidine (68.3 g) were condensed in the same manner as described in Preparation Example 37 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867221B2
Source datasetuspto-grants-2005_03
ORD IDord-f149a3c7ace44158887740ef495a1dee
Source noteuspto-grants-2005_03