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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984243Generated: October 29, 2026

4-Ethoxyaniline → 1-Boc-4-[(4-ethoxyphenyl)amino]-piperidine

https://huagongshe.com/reaction/984243

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-EthoxyanilineHCID 9076—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Product1-Boc-4-[(4-ethoxyphenyl)amino]-piperidineHCID 22557860—

Reaction Steps

1-(tert-butoxycarbonyl)-4-piperidinone (5.00 g) and p-phenetidine (3.28 g) was treated in the same manner as described in Preparation Example 37 to give brown powder of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867221B2
Source datasetuspto-grants-2005_03
ORD IDord-e4f0c7c8b37f4d9cb711ade4a0af57d4
Source noteuspto-grants-2005_03