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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984255Generated: October 29, 2026

2-Methoxyaniline → tert-Butyl 4-((2-methoxyphenyl)amino)piperidine-1-carboxylate

https://huagongshe.com/reaction/984255

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethoxyanilineHCID 7000—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Producttert-Butyl 4-((2-methoxyphenyl)amino)piperidine-1-carboxylateHCID 22557919—

Reaction Steps

1-(tert-Butoxycarbonyl)-4-piperidone (4.78 g) and o-anisidine (2.96 g) were condensed in the same manner as described in Preparation Example 37 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867221B2
Source datasetuspto-grants-2005_03
ORD IDord-0648f59187df44a88b87e435d99b2ee2
Source noteuspto-grants-2005_03