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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984270Generated: October 30, 2026

p-Toluidine → para-methyl 4-Anilino-1-Boc-piperidine

https://huagongshe.com/reaction/984270

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Productpara-methyl 4-Anilino-1-Boc-piperidineHCID 22557837—

Reaction Steps

1-(tert-Butoxycarbonyl)-4-piperidone (5.00 g) and p-toluidine (2.56 g) was treated in the same manner as described in Preparation Example 37 to give white powder of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867221B2
Source datasetuspto-grants-2005_03
ORD IDord-ddbc3a7851f54c78b7064b29702697e4
Source noteuspto-grants-2005_03