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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984312Generated: October 31, 2026

Sodium Hydroxide → HCID 69800487, compound

https://huagongshe.com/reaction/984312

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 69800548HCID 69800548—
SolventEthanolHCID 702—
ProductHCID 69800487HCID 69800487—

Reaction Steps

(S)-2-Ethoxy-3-[4-(3-quinolin-2-yl-allyloxy)-phenyl]-propionic acid ethyl ester (example 41) (150 mg, 0.37 mmol) was dissolved in ethanol (2 mL) and sodium hydroxide (1N, 2.0 mL, 2.0 mmol) added. The mixture was stirred at room temperature for 16 h. The reaction mixture was concentrated in vacuo, added 2-propanol (2 mL) and diethyl ether (2 mL). The title compound was isolated by filtration.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867218B2
Source datasetuspto-grants-2005_03
ORD IDord-86720f8c5a6a40a2a63fe7b4806146b3
Source noteuspto-grants-2005_03