Diisobutylaluminum hydride → HCID 22557552, compound

HRID 984334Notes

Reaction equation

HRID 984334 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5](/[C:8](/[CH3:16])=[C:9](\[CH3:15])/[C:10](OCC)=[O:11])=[CH:4][CH:3]=1.CC(C[AlH]CC(C)C)C>>[Br:1][C:2]1[CH:3]=[CH:4][C:5](/[C:8](/[CH3:16])=[C:9](\[CH3:15])/[CH2:10][OH:11])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 14487Diisobutylaluminum hydrideHCID 86589951HCID 86589951, compound

Product 1

HCID 22557552HCID 22557552, compound

Procedure

(E)-Ethyl 3-(4-bromophenyl)-2-methyl-but-2-enoate (2.83 g, 9.99 mmol) was reduced with DIBAL-H by a procedure analogous to that described in example 52b to give (E)-3-(4-bromophenyl)-2-methyl-but-2-en-1-ol as a colourless oil; 1.82 g (75%).

Sources & evidence

ORD record
ord-5a4ae45d517b4ab58e771d5c69b9a1a4
Source dataset
uspto-grants-2005_03
Patent number
US06867218B2

Reaction notes

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