Diisobutylaluminum hydride → HCID 22557709, compound

HRID 984340Notes

Reaction equation

HRID 984340 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:13]=[CH:12][C:11](/[C:14](/[CH3:19])=[CH:15]/[C:16]([O-])=[O:17])=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.CC(C[AlH]CC(C)C)C>>[CH3:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:13]=[CH:12][C:11](/[C:14](/[CH3:19])=[CH:15]/[CH2:16][OH:17])=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 14487Diisobutylaluminum hydrideHCID 22557694HCID 22557694, compound

Product 1

HCID 22557709HCID 22557709, compound

Procedure

(E)-3-(3′-Methyl-biphenyl-4-yl)-but-2-enoate (0.74 g, 2.64 mmol) was reduced with DIBAL-H by a procedure analogous to that described in example 52 b to give (E)-3-(3′-methyl-biphenyl-4-yl)-but-2-en-1-ol as a colourless solid; 0.63 g (85%).

Sources & evidence

ORD record
ord-df7cf85ba41f41edaf0f66e7627e9e77
Source dataset
uspto-grants-2005_03
Patent number
US06867218B2

Reaction notes

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