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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984359Generated: October 29, 2026

2,5-Dimethoxyphenylboronic acid → (E)-ethyl 3-(2',5'-dimethoxy-biphenyl-4-yl)-but-2-enoate

https://huagongshe.com/reaction/984359

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-Dimethoxyphenylboronic acidHCID 2734342—
Reactant(E)-ethyl 3-(4-bromophenyl)-but-2-enoateHCID 15933615—
Product(E)-ethyl 3-(2',5'-dimethoxy-biphenyl-4-yl)-but-2-enoateHCID 22557594—

Reaction Steps

The colourless oil, (E)-ethyl 3-(2′,5′-dimethoxy-biphenyl-4-yl)-but-2-enoate was prepared from (E)-ethyl 3-(4-bromophenyl)-but-2-enoate (example 50a) and 2,5-dimethoxyphenyl boronic acid by a procedure analogous to that described in example 52a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867218B2
Source datasetuspto-grants-2005_03
ORD IDord-8105724f23a844008f1e0e78700f1a3e
Source noteuspto-grants-2005_03