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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984424Generated: October 30, 2026

Diisobutylaluminum hydride → (E)-3-(4'-fluoro-biphenyl-4-yl)-but-2-en-1-ol

https://huagongshe.com/reaction/984424

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisobutylaluminum hydrideHCID 14487—
Reactant(E)-ethyl 3-(4'-fluoro-biphenyl-4-yl)-but-2-enoateHCID 22557664—
Product(E)-3-(4'-fluoro-biphenyl-4-yl)-but-2-en-1-olHCID 58816048—

Reaction Steps

The colourless solid (E)-3-(4′-fluoro-biphenyl-4-yl)-but-2-en-1-ol was prepared by DIBAL-H reduction of (E)-ethyl 3-(4′-fluoro-biphenyl-4-yl)-but-2-enoate as described for example 52b.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867218B2
Source datasetuspto-grants-2005_03
ORD IDord-c526b4d1f2ee480ab667d545a624491f
Source noteuspto-grants-2005_03