2-Chlorobenzaldehyde → 3'-Chloro-4'-[(2-chlorophenyl)thio]acetophenone

HRID 984463Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[SH:8].ClC1C=CC=CC=1C=O.F[C:19]1[CH:24]=[CH:23][C:22]([C:25](=[O:27])[CH3:26])=[CH:21][C:20]=1[Cl:28]>>[Cl:28][C:20]1[CH:21]=[C:22]([C:25](=[O:27])[CH3:26])[CH:23]=[CH:24][C:19]=1[S:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[Cl:1]

Participants

Reactant 3

HCID 69962-Chlorobenzaldehyde

HCID 80599o-Chlorothiophenol

HCID 5204223'-Chloro-4'-fluoroacetophenone

Product 1

HCID 220231783'-Chloro-4'-[(2-chlorophenyl)thio]acetophenone

Procedure

The title compound was prepared by the procedures described in Example 1A substituting 2,4-dichlorothiophenol with 2-chlorothiophenol, and 2-chlorobenzaldehyde with 4′-fluoro-3′-chloroacetophenone.

Sources & evidence

ORD record: ord-0080f76bef6b450a8917bccadee8bad2
Source dataset: uspto-grants-2005_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06867203B2

Reaction notes

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