HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethane, 2-bromo-1,1-diethoxy- → 2-Amino-5-bromopyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethane, 2-bromo-1,1-diethoxy- | HCID 74852 | — |
| Reactant | 6-Bromoimidazo[1,2-a]pyridine | HCID 2795547 | — |
| Product | 2-Amino-5-bromopyridine | HCID 70622 | — |
| Product | 6-Bromoimidazo[1,2-a]pyridine | HCID 2795547 | — |
Reaction Steps
According to a method known from a literature [M. Yamanaka et al., Chemical & Pharmaceutical Bulletin (Chem. Pharm. Bull.), 1991, vol. 39, p.1556], the title compound (Intermediate 109, 3.36 g) was obtained from commercially available bromoacetaldehyde-diethyl acetal (4.7 ml, WAKO) and 2-amino-5-bromopyridine (4.32 g, Ald). Mass (LCMS): 197 (M+), retention time: 0.73 minutes (elution condition: B).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867320B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-30b518fc681a4e3da7a6051f0c4ff329 |
| Source note | uspto-grants-2005_03 |