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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984990Generated: October 30, 2026

6-(4-Fluoro-3-methylphenyl)-2-isobutyl-4-methane-sulfonyloxymethyl-2H-pyridazin-3-one → 6-(4-Fluoro-3-methylphenyl)-2-isobutyl-4-methylaminomethyl-2h-pyridazin-3-one

https://huagongshe.com/reaction/984990

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(4-Fluoro-3-methylphenyl)-2-isobutyl-4-methane-sulfonyloxymethyl-2H-pyridazin-3-oneHCID 21991457—
Reactant6-(4-fluoro-3-methylphenyl)-2-isobutyl-4-methoxycarbonyl-2H-pyridazin-3-oneHCID 21991533—
Product6-(4-Fluoro-3-methylphenyl)-2-isobutyl-4-methylaminomethyl-2h-pyridazin-3-oneHCID 2199154196.2%

Reaction Steps

Following the procedure of Example 9 (4), 6-(4-fluoro-3-methylphenyl)-2-isobutyl-4-methanesulfonyloxymethyl-2H-pyridazin-3-one was reacted to yield the title compound as a pale yellow oil (yield: 96.2%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06869954B2
Source datasetuspto-grants-2005_03
ORD IDord-32b0c238cef042e9b07b8e9fbd2b4dfa
Source noteuspto-grants-2005_03