2,5-Dimethyl-4-[[2-methyl-4-[(4-trifluoromethyl-phenylamino)methyl]phenyl]sulfanyl]-phenoxy-acetic acid ethyl ester → 2,5-Dimethyl-4-[[2-methyl-4-[(4-trifluoromethyl-phenylamino)methyl]phenyl]sulfanyl]-phenoxy-acetic acid

Participants

Role	Name	HCID	Charge
Reactant	2,5-Dimethyl-4-[[2-methyl-4-[(4-trifluoromethyl-phenylamino)methyl]phenyl]sulfanyl]-phenoxy-acetic acid ethyl ester	HCID 20768106	—
Reactant	4-[[4-[(4-Trifluoromethylphenoxy)methyl]phenyl]sulfanyl]-2-methylphenoxy-acetic acid	HCID 22555039	—
Product	2,5-Dimethyl-4-[[2-methyl-4-[(4-trifluoromethyl-phenylamino)methyl]phenyl]sulfanyl]-phenoxy-acetic acid	HCID 10140359	—

Reaction Steps

The title compound was prepared according to the method described for preparing compound 7, using compound 21.5 as starting material. MS APSI m/e: 474 (M−H). 1H NMR (400 MHz) (DMSO-d6) δ 12.86 (1H, brs); 7.33 (2H, d, J=8.6 Hz); 7.21 (1H, s); 7.12 (1H, s); 7.05 (1H, d, J=8.1 Hz); 6.87 (1H, s); 6.85 (1H, t, J=5.6 Hz); 6.65 (2H, d, J=8.6 Hz); 6.62 (1H, d, J=8.1 Hz); 4.72 (2H, s); 4.22 (2H, d, J=5.6 Hz); 2.30 (3H, s); 2.23 (3H, s); 2.11 (3H, s).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06869975B2
Source dataset	uspto-grants-2005_03
ORD ID	ord-a13b14510f84453a973e7d7eafbd3117
Source note	uspto-grants-2005_03