[4-(2-Chloro-4-formyl-phenylsulfanyl)-2,5-dimethyl-phenoxy]-acetic acid ethyl ester → [4-(2-Chloro-4-hydroxymethyl-phenylsulfanyl)-2,5-dimethyl-phenoxy]-acetic acid ethyl ester

Participants

Role	Name	HCID	Charge
Reactant	[4-(2-Chloro-4-formyl-phenylsulfanyl)-2,5-dimethyl-phenoxy]-acetic acid ethyl ester	HCID 20768115	—
Reactant	4-[(2-Chloro-4-hydroxymethylphenyl)sulfanyl]-2-methylphenoxy-acetic acid ethyl ester	HCID 20768118	—
Product	[4-(2-Chloro-4-hydroxymethyl-phenylsulfanyl)-2,5-dimethyl-phenoxy]-acetic acid ethyl ester	HCID 20768117	—

Reaction Steps

The title compound was prepared according to the method described for preparing compound 10.5, using compound 24.1 as the starting material. 1H NMR (400 MHz) (CDCl3) δ 7.36 (1H, d, J=1.6 Hz); 7.33 (1H, s); 7.01 (1H, dd, J=1.9, 8.1 Hz); 6.67 (1H, s); 6.50 (1H, d, J=8.2 Hz); 4.68 (2H, s); 4.60 (2H, s); 4.30 (2H, q, J=7.2 Hz); 2.31 (3H, s); 2.25 (3H, s); 1.67 (1H, brs); 1.32 (3H, t, J=7.2 Hz).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06869975B2
Source dataset	uspto-grants-2005_03
ORD ID	ord-07189280501341f19d31ae4b41716945
Source note	uspto-grants-2005_03