HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → N,2-Dimethyl-6-(thieno[3,2-b]pyridin-7-yloxy)-3-benzofurancarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 7-Chlorothieno[3,2-b]pyridine | HCID 11275251 | — |
| Reactant | 6-Hydroxy-N,2-dimethylbenzofuran-3-carboxamide | HCID 16755173 | — |
| Product | N,2-Dimethyl-6-(thieno[3,2-b]pyridin-7-yloxy)-3-benzofurancarboxamide | HCID 20767890 | — |
Reaction Steps
This material was prepared by the reaction of 7-chloro-thieno[3,2-b]pyridine with 6-hydroxy-2-methylbenzofuran-3-carboxylic acid methyl amide 12c and Cs2CO3 in a manner as previously described for example 1. 1H NMR (CD3CN) δ8.48 (1H, d, J=5.3 Hz), 7.91 (1H, d, J=5.6 Hz), 7.84 (1H, d, J=8.6 Hz), 7.53 (1H, d, J=5.6 Hz), 7.41 (1H, d, J=2.0 Hz), 7.20 (1H, dd, J=8.6, 2.0 Hz), 6.62 (1H, d, J=5.3 Hz), 6.60 (1H, bm), 2.91 (3H, d, J=4.6 Hz) 2.66 (3H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06869962B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-f2385dd4a4b54da48d70b4bf7d2bc777 |
| Source note | uspto-grants-2005_03 |