Hydrochloric Acid → HCID 22506966, compound

Participants

Reaction Steps

A mixture of 3-(4-fluoro-phenylsulfanyl)-6-methoxy-pyridazine (250 mg), prepared by a procedure analogous to step A of Example 2, and concentrated hydrochloric acid was prepared and refluxed for 30 minutes. The mixture was then evaporated to dryness. The resulting residue was purified by silica gel chromatography (ethyl acetate as eluent) to afford the title compound (65%, 152 mg); mp, 99-101° C.

Provenance & Evidence