Trifluoroacetic acid → (2R)-2-Amino-3-phenylpropyl 2,2-dimethylpropanoate

Participants

Reaction Steps

A cooled solution of compound 94 (1.006 g, 3 mmol) in CH2Cl2 (10 ml) at 0° C. was treated with trifluoroacetic acid (2.5 ml) and stirred for 1 hr at room temperature. The mixture was concentrated in vacuo to give compound 96 as a yellow oil which was used for the next step without further purification.

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