Triethylamine → 4-chloro-N-[5-chloro-2-(6-fluoro-2,3-dihydro-benzo[1,4]oxazine-4-carbonyl)-pyridin-3-yl]-3-trifluoromethyl-benzenesulfonamide

HRID 98563Notes

Reaction equation

HRID 98563 reaction equation
[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[Cl:1][c:2]1[cH:3][c:4]([NH:11][S:12](=[O:13])(=[O:14])[c:15]2[cH:16][c:17]([C:22]([F:23])([F:24])[F:25])[c:18]([Cl:21])[cH:19][cH:20]2)[c:5]([C:8](=[O:9])[OH:10])[n:6][cH:7]1.[F:26][c:27]1[cH:28][cH:29][c:30]2[c:31]([cH:36]1)[NH:32][CH2:33][CH2:34][O:35]2>>[Cl:1][c:2]1[cH:3][c:4]([NH:11][S:12](=[O:13])(=[O:14])[c:15]2[cH:16][c:17]([C:22]([F:23])([F:24])[F:25])[c:18]([Cl:21])[cH:19][cH:20]2)[c:5]([C:8](=[O:9])[N:32]2[c:31]3[c:30]([cH:29][cH:28][c:27]([F:26])[cH:36]3)[O:35][CH2:34][CH2:33]2)[n:6][cH:7]1

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 162444596-Fluoro-3,4-dihydro-2H-1,4-benzoxazineHCID 579420775-Chloro-3-(4-chloro-3-trifluoromethyl benzenesulfonylamino)-pyridine-2-carboxylic acid

Product 1

HCID 441770744-chloro-N-[5-chloro-2-(6-fluoro-2,3-dihydro-benzo[1,4]oxazine-4-carbonyl)-pyridin-3-yl]-3-trifluoromethyl-benzenesulfonamide

Sources & evidence

ORD record
ord-071e7b151ed744948f4fcfd399fb50ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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