HRID985634

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cc1cn([C@H]2C[C@H](O)[C@@H](CN=[N+]=[N-])O2)c(=O)[nH]c1=O

HCID451456

Thymidine, 5'-azido-5'-deoxy-

C10H13N5O4

PRODUCTS

生成物

结构：Cc1cn([C@H]2C[C@H](O)[C@@H](CN)O2)c(=O)[nH]c1=O

HCID65311

THYMIDINE, 5'-AMINO-5'-DEOXY-

C10H15N3O4

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID178418361

未命名化合物

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

The thus-obtained 5′-azido-5′-deoxythymidine was then dissolved in methanol and reduced with hydrogen using 10% palladium/carbon as a catalyst, whereby 5′-amino-5′-deoxythymidine was obtained. Yield 1.734 g, 71.6%.