HCID 21917012, compound → HCID 9845508, compound

HRID 985769Notes

Reaction equation

HRID 985769 reaction equation
[F:1][C:2]([F:33])([F:32])[C:3]1[CH:4]=[C:5]([CH:29]=[CH:30][CH:31]=1)[C:6]([NH:8][CH2:9][CH2:10][C:11]1[CH:12]=[CH:13][CH:14]=[C:15]2[C:20]=1[CH:19]=[C:18]([S:21]([CH2:24][CH2:25][C:26](O)=[O:27])(=O)=O)[CH:17]=[CH:16]2)=[O:7]>S(Cl)(Cl)=O>[O:27]=[C:26]1[C:19]2[C:20]3[C:11]([CH2:10][CH2:9][NH:8][C:6](=[O:7])[C:5]4[CH:29]=[CH:30][CH:31]=[C:3]([C:2]([F:32])([F:33])[F:1])[CH:4]=4)=[CH:12][CH:13]=[CH:14][C:15]=3[CH:16]=[CH:17][C:18]=2[S:21][CH2:24][CH2:25]1

Participants

3

Reactant 1

HCID 21917012HCID 21917012, compound

Product 1

HCID 9845508HCID 9845508, compound

Reagents, catalysts & solvents 1

HCID 24386Thionyl ChlorideSolvent

Conditions

Temperature
60 °C

Procedure

The product obtained in Step B (3 mmol), dissolved in thionyl chloride, is stirred at 60° C. under a current of nitrogen for one hour. The thionyl chloride is evaporated off under reduced pressure and the residue is dried with the aid of a vane pump to yield the title product.

Workup

  1. customThe thionyl chloride is evaporated off under reduced pressure
  2. customthe residue is dried with the aid of a vane pump

Sources & evidence

ORD record
ord-fd3582b2f9824d81a216a6449aff4b97
Source dataset
uspto-grants-2005_03
Patent number
US06872851B1

Reaction notes

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