HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-chloroacetoacetate → Methyl (R)-4-Chloro-3-hydroxybutyrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-chloroacetoacetate | HCID 36240 | — |
| Reactant | Nadh | HCID 439153 | — |
| Solvent | Trisodium Phosphate | HCID 24243 | — |
| Product | Methyl (R)-4-Chloro-3-hydroxybutyrate | HCID 10920707 | — |
Reaction Steps
Methyl-4-chloroacetoacetate (VII) (100 mg) was incubated with 29 units of porcine heart (EC 1.1.1.35), B-hydroxyacyl CoA dehydrogenase (Sigma, H4626), and 1.36 g of NADH (Sigma, 90%) in 30 ml of 0.1 M sodium phosphate buffer, pH 6.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04710468 |
| Source dataset | uspto-grants-1987_12 |
| ORD ID | ord-57a389a067644a3f99aec4750d3b1ed5 |
| Source note | uspto-grants-1987_12 |