O-Allylhydroxylamine hydrochloride → HCID 53692053, compound

HRID 986030Notes

Reaction equation

HRID 986030 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]=[C:4]([CH2:8][C:9](=O)[CH3:10])[CH2:3]1.Cl.[CH2:13]([O:16][NH2:17])[CH:14]=[CH2:15]>C(O)C>[CH2:13]([O:16][N:17]=[C:8]([C:4]1[CH2:3][N:2]([CH3:1])[CH2:7][CH2:6][CH:5]=1)[CH2:9][CH3:10])[CH:14]=[CH2:15]

Participants

4

Reactant 2

HCID 3084724O-Allylhydroxylamine hydrochlorideHCID 57075564HCID 57075564, compound

Product 1

HCID 53692053HCID 53692053, compoundYield 53%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1-(1,2,5,6-Tetrahydro-1-methyl-3-pyridinyl)propanone (3.06 g, 20 mmol, prepared as described in Example 8 above) was reacted with 3.27 g (30 mmol) of O-2-propenylhydroxylamine hydrochloride in 20 ml of ethanol to prepare 2.2 g (53%) of the title compound, isolated as the ethanedioate salt, mp 117°-120° C.

Sources & evidence

ORD record
ord-c058afdb165f4a4ba5da25c51d2b6bf6
Source dataset
uspto-grants-1987_12
Patent number
US04710508

Reaction notes

Loading…