Acetyl chloride → HCID 21284374, compound

HRID 986032Notes

Reaction equation

HRID 986032 reaction equation
C[N:2]1[CH2:7][CH:6]=[C:5]([C:8](=NO)[CH3:9])[CH2:4][CH2:3]1.C(Cl)(=[O:14])C>C(N(CC)CC)C>[NH:2]1[CH2:7][CH:6]=[C:5]([C:8](=[O:14])[CH3:9])[CH2:4][CH2:3]1

Participants

4

Reactant 2

HCID 6367Acetyl chlorideHCID 86250420HCID 86250420, compound

Product 1

HCID 21284374HCID 21284374, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

A mixture of 7.66 g of 1-(1,2,3,6-tetrahydro-1-methyl-4-pyridinyl)ethanone oxime, 6.8 ml of triethylamine, and 3.8 ml of acetyl chloride were stirred at room temperature overnight under a nitrogen atmosphere. Isolation of the product in the conventional manner produced 8.07 g of 1-(1,2,3,6-tetrahydro-4-pyridinyl)ethanone, O-acetyloxime which was converted to the hydrochloride salt, mp 104.5°-105.5° C.

Sources & evidence

ORD record
ord-56cda14af08443b5a6b8b95e61e41a1e
Source dataset
uspto-grants-1987_12
Patent number
US04710508

Reaction notes

Loading…