Toluene → HCID 14376313, compound

HRID 986182Notes

Reaction equation

HRID 986182 reaction equation
[CH3:1][N:2]([CH3:4])[CH3:3].[S:5]([C:9]1[CH:15]=[CH:14][C:12]([CH3:13])=[CH:11][CH:10]=1)([O-:8])(=[O:7])=[O:6].[C:16]1([CH3:22])C=CC=C[CH:17]=1>>[S:5]([C:9]1[CH:15]=[CH:14][C:12]([CH3:13])=[CH:11][CH:10]=1)([O-:8])(=[O:7])=[O:6].[OH:6][CH2:17][CH2:16][CH2:22][N+:2]([CH3:4])([CH3:3])[CH3:1]

Participants

4

Reactant 3

HCID 1140TolueneHCID 1146TrimethylamineHCID 85570p-Toluenesulfonate

Product 1

HCID 14376313HCID 14376313, compoundYield 92%

Procedure

7 ml of 18% trimethylamine in toluene was added to 2.0 g (9.2 mmole) of the above tosylate, and the mixture was allowed to stand at room temperature for 3 days. The crystals separated out were collected by filtration, washed with toluene and dried under reduced pressure to give 3-hydroxypropyltrimethylammonium tosylate as colorless needles. Melting point: 80° C. Yield: 2.3 g (yield: 92%).

Workup

  1. customThe crystals separated out
  2. filtrationwere collected by filtration
  3. washwashed with toluene
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-f4553acb62e446f4994425ddc370e798
Source dataset
uspto-grants-1987_12
Patent number
US04710579

Reaction notes

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