Hydrochloric Acid → HCID 178479735, compound

Participants

Reaction Conditions

Reaction Steps

An intimate mixture of 1-phenoxy-3-β-aminoethylamino-2-propanol (4.2 g.) and ethyl 4-mercaptophthalazine-4-carboxylate (2.3 g.) is heated at 95° C. for 1 hour, cooled, powdered and stirred with a mixture of aqueous 2N-hydrochloric acid and ether. The mixture is filtered and there is thus obtained as solid residue 1-phenoxy-3-β-(4-mercaptophthalazine-1-carboxamido)ethylamino-2-propanol hydrochloride, m.p. 232°-236° C., which is used without further purification.

Provenance & Evidence