5-Nitrofurfural → 3-(6-Methoxy-3-pyridyl)-2-propenoic acid [(5-nitro-2-furyl)methylene]hydrazide

HRID 986222Notes

Reaction equation

HRID 986222 reaction equation
[CH3:1][O:2][C:3]1[N:8]=[CH:7][C:6]([CH:9]=[CH:10][C:11]([NH:13][NH2:14])=[O:12])=[CH:5][CH:4]=1.[N+:15]([C:18]1[O:22][C:21]([CH:23]=O)=[CH:20][CH:19]=1)([O-:17])=[O:16]>CO>[N+:15]([C:18]1[O:22][C:21]([CH:23]=[N:14][NH:13][C:11](=[O:12])[CH:10]=[CH:9][C:6]2[CH:7]=[N:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[CH:20][CH:19]=1)([O-:17])=[O:16]

Participants

4

Reactant 2

HCID 127745-NitrofurfuralHCID 704352203-(6-Methoxy-3-pyridyl)-2-propenoic acid hydrazide

Product 1

HCID 537963563-(6-Methoxy-3-pyridyl)-2-propenoic acid [(5-nitro-2-furyl)methylene]hydrazide

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution, heated to 50°-60° C., of 0.9 g (4.66 mmol) of 3-(6-methoxy-3-pyridyl)-2-propenoic acid hydrazide in 50 ml of methanol, 0.66g (4.7 mmol) of 5-nitrofuran-2-carbaldehyde is added.

Workup

  1. additionis added

Sources & evidence

ORD record
ord-78e719a269844994ab187c3db866ba4a
Source dataset
uspto-grants-1987_12
Patent number
US04711892

Reaction notes

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