Potassium Carbonate → 2-{4-[2-(4-Fluorophenyl)-1,3-dioxolan-2-yl]-1-piperidyl}-1-(4-fluorophenyl)-1-propanone

Participants

Role	Name	HCID	Charge
Reactant	Potassium Carbonate	HCID 11430	—
Reactant	2-Bromo-1-(4-fluorophenyl)propan-1-one	HCID 13051652	—
Reactant	2-(4-Fluorophenyl)-2-(4-piperidyl)1,3-dioxolane	HCID 13279099	—
Solvent	Acetonitrile	HCID 6342	—
Product	2-{4-[2-(4-Fluorophenyl)-1,3-dioxolan-2-yl]-1-piperidyl}-1-(4-fluorophenyl)-1-propanone	HCID 20158459	—

Reaction Steps

The reaction is performed under the conditions of Example 4a, starting with 9.24 g (0.04 mole) of 2-bromo-1-(4-fluorophenyl)-1-propanone, 10.05 g (0.04 mole) of 2-(4-fluorophenyl)-2-(4-piperidyl)1,3-dioxolane and 5.56 g of potassium carbonate in 150 ml of acetonitrile.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US04711899
Source dataset	uspto-grants-1987_12
ORD ID	ord-8b283410461c45ed90d138e288973eb1
Source note	uspto-grants-1987_12