HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Methylmorpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Boc-L-phenylalaninamide | HCID 7020416 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Methylmorpholine | HCID 7972 | — |
| Product | Phenylalanine amide hydrochloride | HCID 11953719 | — |
Reaction Steps
Two minutes later, a solution of PheNH2HCl (1.2 g, 0.6 mmol), obtained by cleavage of the t-butoxycarbonyl group from BocPheNH2 with 4.5N HCl in EtOAc, and NMM (0.6 g, 6 mmoles) in DMF is added thereto.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04713367 |
| Source dataset | uspto-grants-1987_12 |
| ORD ID | ord-15d54b42db1843fa8f2350d08cfc59bf |
| Source note | uspto-grants-1987_12 |