Ethylamine → HCID 178463639, compound

Participants

Reaction Steps

2-(2-Furyl)-5-methylthio-[1,2,4]triazolo[1,5-c]quinazoline (1.41 g) is placed in a stainless steel pressure vessel with ethanol (200 ml) and 70% aqueous ethylamine (100 ml) and heated to an outside temperature of 150°. It reaches a pressure of 100 p.s.i. and is maintained at that pressure and temperature for 16 hours. It is cooled and the material concentrated to dryness at reduced pressure The residual solid is recrystallized from methanol to afford pure 5-ethylimino-2-(2-furyl)-5,6-dihydro-[1,2,4]triazolo[1,5-c]quinazoline, mp 133°-135°.

Provenance & Evidence