Water → HCID 14031943, compound

Participants

Reaction Steps

A solution of 9-chloro-5-thiocyanato-2-(2-furyl)[1,2,4]triazolo-[1,5-c]quinazoline (2 g) in 1,3-dimethylimidazolidone (28 ml) is added to tert-butylamine (2 ml). The mixture is stirred for 3 hours under nitrogen, and then is diluted with ethanol (20 ml), and treated with water (20 ml). The resulting precipitate is collected, recrystallized from 2-methoxyethanol, and dried in high vacuum to afford pure 5-tert-butylamino-9-chloro-2-(2-furyl)-[1,2,4]triazolo-[1,5-c]quinazoline, mp above 330° C.

Provenance & Evidence