Piperazine → HCID 13592657, compound

HRID 986622Notes

Reaction equation

HRID 986622 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:15]2[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][CH3:14])[C:6]=2[N:7]=1.[NH:21]1[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1>CS(C)=O>[CH2:13]([S:12][C:8]1[C:6]2[N:7]=[C:2]([N:21]3[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]3)[N:3]=[C:4]([N:15]3[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]3)[C:5]=2[N:11]=[CH:10][N:9]=1)[CH3:14]

Participants

4

Reactant 2

HCID 4837PiperazineHCID 13592632HCID 13592632, compound

Product 1

HCID 13592657HCID 13592657, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

Prepared analogously to Example 2 from 2-chloro-8-ethylthio-4-piperidino-pyrimido[5,4-d]pyrimidine and piperazine in dimethylsulphoxide.

Sources & evidence

ORD record
ord-90a9cdf5f0984efbb4c2523f2e469b87
Source dataset
uspto-grants-1987_12
Patent number
US04714698

Reaction notes

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