Piperazine → HCID 13592658, compound

HRID 986623Notes

Reaction equation

HRID 986623 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][CH2:14][CH3:15])[C:6]=2[N:7]=1.[NH:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1>CS(C)=O>[N:16]1([C:4]2[C:5]3[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][CH2:14][CH3:15])[C:6]=3[N:7]=[C:2]([N:22]3[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]3)[N:3]=2)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1

Participants

4

Reactant 2

HCID 4837PiperazineHCID 13592633HCID 13592633, compound

Product 1

HCID 13592658HCID 13592658, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

Prepared analogously to Example 2 from 2-chloro-4-piperidino-8-n-propylthio-pyrimido[5,4-d]pyrimidine and piperazine in dimethylsulphoxide.

Sources & evidence

ORD record
ord-710ff7a08d3b4b96a5c8aa6f96473a02
Source dataset
uspto-grants-1987_12
Patent number
US04714698

Reaction notes

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