Piperazine → HCID 13592652, compound

HRID 986625Notes

Reaction equation

HRID 986625 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:14]([CH3:22])[CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH3:13])[C:6]=2[N:7]=1.[NH:23]1[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]1>CS(C)=O>[CH2:15]([N:14]([CH3:22])[C:4]1[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH3:13])[C:6]=2[N:7]=[C:2]([N:23]2[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]2)[N:3]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

4

Reactant 2

HCID 4837PiperazineHCID 13592640HCID 13592640, compound

Product 1

HCID 13592652HCID 13592652, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

Prepared analogously to Example 2 from 2-chloro-4-(N-benzyl-methylamino)-8-methylthio-pyrimido[5,4-d]pyrimidine and piperazine in dimethylsulphoxide.

Sources & evidence

ORD record
ord-a75c5c5329594390905c53bbdc7e4f27
Source dataset
uspto-grants-1987_12
Patent number
US04714698

Reaction notes

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