Piperazine → HCID 13592653, compound

HRID 986626Notes

Reaction equation

HRID 986626 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:14]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH3:15])[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH3:13])[C:6]=2[N:7]=1.[NH:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1>CS(C)=O>[CH3:15][N:14]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:4]1[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH3:13])[C:6]=2[N:7]=[C:2]([N:22]2[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]2)[N:3]=1

Participants

4

Reactant 2

HCID 4837PiperazineHCID 13592641HCID 13592641, compound

Product 1

HCID 13592653HCID 13592653, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

Prepared analogously to Example 2 from 2-chloro-4-(N-methyl-phenylamino)-8-methylthio-pyrimido[5,4-d]pyrimidine and piperazine in dimethylsulphoxide.

Sources & evidence

ORD record
ord-f06d5e9504144d0283c040b06a073600
Source dataset
uspto-grants-1987_12
Patent number
US04714698

Reaction notes

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