HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromobenzoic acid → 2-Bromobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromobenzoic acid | HCID 6940 | — |
| Reactant | Phosphorus trichloride | HCID 24387 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Solvent | 1,1-Dichloroethane | HCID 6365 | — |
| Product | 2-Bromobenzoyl chloride | HCID 23542 | — |
Reaction Steps
To a mixture of 50.2 g (0.25 mole) of 2-bromobenzoic acid in 200 ml of 1,2-dichloroethane was added 13.7 g (0.10 mole) of phosphorous trichloride in 100 ml of dichloroethane. The mixture was heated at reflux for 4 hours to provide 2-bromobenzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04714776 |
| Source dataset | uspto-grants-1987_12 |
| ORD ID | ord-69b8ce3f0d714b66a10dad4351385c71 |
| Source note | uspto-grants-1987_12 |