2-Bromobenzoic acid → 2-Bromobenzoyl chloride

HRID 986684Notes

Reaction equation

HRID 986684 reaction equation
[Br:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](O)=[O:5].P(Cl)(Cl)[Cl:12]>ClCCCl.ClC(Cl)C>[Br:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([Cl:12])=[O:5]

Participants

5

Reactant 2

HCID 69402-Bromobenzoic acidHCID 24387Phosphorus trichloride

Product 1

HCID 235422-Bromobenzoyl chloride

Reagents, catalysts & solvents 2

HCID 111,2-DichloroethaneSolventHCID 63651,1-DichloroethaneSolvent

Procedure

To a mixture of 50.2 g (0.25 mole) of 2-bromobenzoic acid in 200 ml of 1,2-dichloroethane was added 13.7 g (0.10 mole) of phosphorous trichloride in 100 ml of dichloroethane. The mixture was heated at reflux for 4 hours to provide 2-bromobenzoyl chloride.

Workup

  1. temperatureThe mixture was heated
  2. temperatureat reflux for 4 hours

Sources & evidence

ORD record
ord-69b8ce3f0d714b66a10dad4351385c71
Source dataset
uspto-grants-1987_12
Patent number
US04714776

Reaction notes

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