Methanesulfonyl chloride → HCID 20156425, compound

Participants

Reaction Steps

0.3 g (1.17 mmol) of 2-(2-Methoxy-4-hydroxyphenyl)-5H-imidazo[1,2-b]pyridazin-6-one are dissolved in 10 ml of 1N sodium hydroxide solution. At 20° C., 1.3 g (1.17 mmol) of methanesulphonic acid chloride is added dropwise. By simultaneously adding 2N sodium hydroxide solution the pH is kept at 10-11.

Provenance & Evidence