Sodium Hydroxide → HCID 20156655, compound

HRID 986854Notes

Reaction equation

HRID 986854 reaction equation
[NH2:1][CH:2]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]([C:18]1[CH:23]=[CH:22][C:21]([NH2:24])=[CH:20][CH:19]=1)([CH3:17])[CH2:15][CH3:16])[CH:3]([CH3:5])[CH3:4].[NH2:25][CH:26]([CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][C:39]([C:42]1[CH:47]=[CH:46][C:45]([NH2:48])=[CH:44][CH:43]=1)([CH3:41])[CH3:40])[CH:27]([CH3:29])[CH3:28].[H][H].[OH-].[Na+]>Cl>[NH2:1][CH:2]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]([CH:18]1[CH2:23][CH2:22][CH:21]([NH2:24])[CH2:20][CH2:19]1)([CH3:17])[CH2:15][CH3:16])[CH:3]([CH3:5])[CH3:4].[NH2:25][CH:26]([CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][C:39]([CH:42]1[CH2:47][CH2:46][CH:45]([NH2:48])[CH2:44][CH2:43]1)([CH3:41])[CH3:40])[CH:27]([CH3:29])[CH3:28]

Participants

7

Reactant 4

HCID 14798Sodium HydroxideHCID 20156676HCID 20156676, compoundHCID 20156702HCID 20156702, compoundHCID 178418361HCID 178418361, compound

Product 2

HCID 20156655HCID 20156655, compoundHCID 20156667HCID 20156667, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

5.0 parts of a mixture of 3-amino-12-(4-aminophenyl)-2,12-dimethyl-tetradecane and 3-amino-13-(4-aminophenyl)-2,13-dimethyltetradecane in 60 ml 1N aqueous hydrochloric acid, were shaken at room temperature and atmospheric pressure in the presence of 1.0 parts of Nishimura catalyst. After the hydrogen uptaken had ceased at 118% of the theory, the solution was made alkaline with caustic soda. The work up was completed after an ether extraction, filtration, and short path distillation, giving 3.4 parts of 3-amino-12-(4-aminocyclohexyl)-2,12-dimethyltetradecane and 3-amino-13-(4-aminocyclohexyl)-2,13-dimethyltetradecane, b0.3 190°.

Workup

  1. extractionafter an ether extraction, filtration, and short path distillation

Sources & evidence

ORD record
ord-6a09cd7adcc74aa3aa48c5331e0f6aaa
Source dataset
uspto-grants-1987_12
Patent number
US04716248

Reaction notes

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