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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 987Generated: October 27, 2026

1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazine → 5-[3-(4-(4-(4-Fluorophenyl)methylphenyl)piperazin-1-yl)propyl]sulfonyl-2,3,4,5-tetrahydro-1,5-benzoxazepine

https://huagongshe.com/reaction/987

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazineHCID 1519998—
Reactant5-(3-Chloropropylsulfonyl)-2,3,4,5-tetrahydro-1,5-benzoxazepineHCID 19694277—
Product5-[3-(4-(4-(4-Fluorophenyl)methylphenyl)piperazin-1-yl)propyl]sulfonyl-2,3,4,5-tetrahydro-1,5-benzoxazepineHCID 19694247—

Reaction Steps

The compound (17) synthesized in Reference Example 17 and the compound (5) synthesized in Reference Example 5 were used to produce the above compound in the same way as Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05723475
Source datasetuspto-grants-1998_03
ORD IDord-9fdee47e3af1400fb5eacb1be913c88c
Source noteuspto-grants-1998_03