2-Nitrobenzaldehyde → N-[(2-Nitrophenyl)methylidene]hydroxylamine

HRID 987003Notes

Reaction equation

HRID 987003 reaction equation
[N+:1]([C:4]1[CH:11]=[CH:10][CH:9]=[CH:8][C:5]=1[CH:6]=O)([O-:3])=[O:2].Cl.[NH2:13][OH:14].C([O-])(=O)C.[Na+]>C(O)C.O>[N+:1]([C:4]1[CH:11]=[CH:10][CH:9]=[CH:8][C:5]=1[CH:6]=[N:13][OH:14])([O-:3])=[O:2]

Participants

6

Reactant 3

HCID 111012-NitrobenzaldehydeHCID 443297Hydroxyamine hydrochlorideHCID 517045Sodium Acetate

Product 1

HCID 96097N-[(2-Nitrophenyl)methylidene]hydroxylamine

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent2×

Procedure

To a solution of 2-nitrobenzaldehyde (115 g) and hydroxylamine hydrochloride (6.6 g) in ethanol (110 ml) and water (4 ml) was added sodium acetate (13.6 g) and the mixture was stirred at room temperature for 4 hours. The mixture was poured into water (500 ml) and the mixture filtered to give the title product.

Workup

  1. filtrationthe mixture filtered

Sources & evidence

ORD record
ord-000f022ef55f48098fe4d5b42b334039
Source dataset
uspto-grants-2003_10
Patent number
US06630495B1

Reaction notes

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