2-Bromomethylnaphthalene → HCID 22988148, compound

HRID 987067Notes

Reaction equation

HRID 987067 reaction equation
[CH3:1][C:2]1[NH:3][CH:4]=[C:5]([C:7]([O:9][CH2:10][CH3:11])=[O:8])[N:6]=1.Br[CH2:13][C:14]1[CH:23]=[CH:22][C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH:15]=1>>[CH3:1][C:2]1[N:3]([CH2:13][C:14]2[CH:23]=[CH:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH:15]=2)[CH:4]=[C:5]([C:7]([O:9][CH2:10][CH3:11])=[O:8])[N:6]=1

Participants

3

Reactant 2

HCID 703202-BromomethylnaphthaleneHCID 178469895HCID 178469895, compound

Product 1

HCID 22988148HCID 22988148, compoundYield 65%

Procedure

4.6 g (29.8 mmol) of ethyl 2-methylimidazole-4-carboxylate and 6.6 g (29.8 mmol) of 2-bromomethylnaphthalene were reacted analogously to procedure 8a. 5.7 g (65%) of the product were obtained.

Sources & evidence

ORD record
ord-c90419063d794de18e453e6c4d7f8aa3
Source dataset
uspto-grants-2003_10
Patent number
US06630493B1

Reaction notes

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