Hydrochloric Acid → HCID 12138349, compound

Participants

Reaction Steps

Methyl 3,5-bis(dimethylcarbamoylthio)benzoate (34.2 g, 0.10 mol) was made to react with a mixture of 43 g of 28% methanol solution of sodium methoxide (0.223 mol) and methanol (150 ml) at 22-25° C. After addition of 500 ml of ice-water, the reaction mixture was neutralized with concentrated hydrochloric acid to give a colorless crystals. The crystals thus obtained were purified by means of recrystallization from methanol giving 12.5 g (62.5%) of methyl 3,5-dimercaptobenzoate as a colorless powder. The melting point is 61-62° C.

Provenance & Evidence