2,2,2-Trifluoroethanol → Fluoroformic acid 2,2,2-trifluoroethyl ester

HRID 987356Notes

Reaction equation

[F:1][C:2]([F:6])([F:5])[CH2:3][OH:4].[C:7](F)([F:9])=[O:8]>>[C:2]([CH2:3][O:4][C:7]([F:9])=[O:8])([F:6])([F:5])[F:1]

Participants

Reactant 2

HCID 64092,2,2-Trifluoroethanol

HCID 9623Carbonyl fluoride

Product 1

HCID 14493380Fluoroformic acid 2,2,2-trifluoroethyl ester

Procedure

236faE (CAS Reg. No. 20193-67-3) has been prepared by reaction of 2,2,2-trifluoroethanol with carbonyl fluoride to give the intermediate, CF3CH2OCOF, which was in turn reacted with sulfur tetrafluoride at 150-200° C. to give the product as disclosed by Eisemann in U.S. Pat. No. 3,394,878.

Sources & evidence

ORD record: ord-09e5a8ab03ac4d67a879d3429af60f71
Source dataset: uspto-grants-2003_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06632376B2

Reaction notes

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