HuagongsheHuagongshe Chemistry Print Report · For research reference only
[3-nitro-4-(trifluoromethyl)phenyl]methanol → [3-amino-4-(trifluoromethyl)phenyl]methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [3-nitro-4-(trifluoromethyl)phenyl]methanol | HCID 11287467 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | [3-amino-4-(trifluoromethyl)phenyl]methanol | HCID 11171505 | 86.8% |
Reaction Steps
The product from Example 4A (3.6 g, 16.28 mmol) in methanol (100 mL) was hydrogenated in the presence of a catalytic amount of Pd /C for 4 hours. The catalyst was filtered off and the volatiles were evaporated to yield 2.7 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06632418B2 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-194c1c009b30450cb99fbf0dda96abe5 |
| Source note | uspto-grants-2003_10 |