Piperazine → HCID 12108585, compound

HRID 987423Notes

Reaction equation

HRID 987423 reaction equation
CS(OCCC[C:9]1[CH:18]=[CH:17][C:16]2[C:11](=[CH:12][C:13]([O:23][CH3:24])=[C:14]([O:21][CH3:22])[C:15]=2[O:19][CH3:20])[CH:10]=1)(=O)=O.[NH:25]1[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1>>[CH3:20][O:19][C:15]1[C:14]([O:21][CH3:22])=[C:13]([O:23][CH3:24])[CH:12]=[C:11]2[C:16]=1[CH:17]=[CH:18][C:9]([CH2:10][CH2:9][CH2:18][N:25]1[CH2:30][CH2:29][N:28]([CH2:12][CH2:11][CH2:16][C:9]3[CH:18]=[CH:17][C:16]4[C:11](=[CH:12][C:13]([O:23][CH3:24])=[C:14]([O:21][CH3:22])[C:15]=4[O:19][CH3:20])[CH:10]=3)[CH2:27][CH2:26]1)=[CH:10]2

Participants

3

Reactant 2

HCID 4837PiperazineHCID 21891653HCID 21891653, compound

Product 1

HCID 12108585HCID 12108585, compound

Procedure

2-(3-Methanesulfonyloxypropyl)-5,6,7-trimethoxynaphthalene (213 mg) and piperazine (26 mg) were reacted in the same manner in Example 1 to obtain the title compound as a free base.

Sources & evidence

ORD record
ord-a4934b9625524ac7a0fd8bea233bd507
Source dataset
uspto-grants-2003_10
Patent number
US06632810B2

Reaction notes

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