反应详情

2-Hydroxymethyl-1-methyl-4,5,6-trimethoxyindole (861 mg) was dissolved in benzene (50 mL), activated manganese dioxide (8.7 g) was added to the solution, and the mixture was stirred at room temperature for 2 hours. After the reaction mixture was filtered, and the filtrate was concentrated, the residue was purified by column chromatography on silica gel (ethyl acetate:hexane=1:2) to obtain the title compound.

1. filtrationAfter the reaction mixture was filtered
2. concentrationthe filtrate was concentrated
3. customthe residue was purified by column chromatography on silica gel (ethyl acetate:hexane=1:2)